产品货号：
Z29364
中文名称：
UGT1A1抗体
英文名称：
Anti-UGT1A1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UGT1A1 Antibody |
| 指标别名 | GNT1;HUG BR1;UDPGT;UDPGT 1 1;UGT 1A;UGT1;UGT1 01;UGT1*1;UGT1.1;UGT1A;UGT1A1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | UGT1A1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human UGT1A1 recombinant protein (Position:E316-H533). |
| 实际分子量 | 59KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the UGT1A1 gene.This gene encodes a UDP-glucuronosyltransferase,an enzyme of the glucuronidation pathway that transforms small lipophilic molecules,such as steroids,bilirubin,hormones,and drugs,into water-soluble,excretable metabolites.This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases.The locus includes thirteen unique alternate first exons followed by four common exons.Four of the alternate first exons are considered pseudogenes.Each of the remaining nine 5' exons may be spliced to the four common exons,resulting in nine proteins with different N-termini and identical C-termini.Each first exon encodes the substrate binding site,and is regulated by its own promoter.The preferred substrate of this enzyme is bilirubin,although it also has moderate activity with simple phenols,flavones,and C18 steroids.Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. |
| Uniprot ID | P22309 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：UGT1A1抗体，UGT1A1多抗，Anti-UGT1A1 Antibody